Cargando…
A type I IFN–Flt3 ligand axis augments plasmacytoid dendritic cell development from common lymphoid progenitors
During infections and inflammation, plasmacytoid dendritic cells (pDCs) are the most potent type I interferon (IFN-I)–producing cells. However, the developmental origin of pDCs and the signals dictating pDC generation remain incompletely understood. Here, we report a synergistic role for IFN-I and F...
Autores principales: | Chen, Yi-Ling, Chen, Ting-Ting, Pai, Li-Mei, Wesoly, Joanna, Bluyssen, Hans A.R., Lee, Chien-Kuo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832917/ https://www.ncbi.nlm.nih.gov/pubmed/24145513 http://dx.doi.org/10.1084/jem.20130536 |
Ejemplares similares
-
Efficient Generation of Plasmacytoid Dendritic Cell from Common Lymphoid Progenitors by Flt3 Ligand
por: Chen, Yi-Ling, et al.
Publicado: (2015) -
The Development of Murine Plasmacytoid Dendritic Cell Precursors Is Differentially Regulated by FLT3-ligand and Granulocyte/Macrophage Colony-Stimulating Factor
por: Gilliet, Michel, et al.
Publicado: (2002) -
Role of ChemR23 in directing the migration of myeloid and plasmacytoid dendritic cells to lymphoid organs and inflamed skin
por: Vermi, William, et al.
Publicado: (2005) -
Flt3 Ligand Regulates Dendritic Cell Development from Flt3(+) Lymphoid and Myeloid-committed Progenitors to Flt3(+) Dendritic Cells In Vivo
por: Karsunky, Holger, et al.
Publicado: (2003) -
Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation
por: Gotoh, Kazuhito, et al.
Publicado: (2010)