Cargando…
The cohesin complex regulates immunoglobulin class switch recombination
Immunoglobulin (Ig) class switch recombination (CSR) is initiated by the transcription-coupled recruitment of activation-induced cytidine deaminase (AID) to switch regions and by the subsequent generation of double-stranded DNA breaks (DSBs). These DNA breaks are ultimately resolved through the nonh...
Autores principales: | Thomas-Claudepierre, Anne-Sophie, Schiavo, Ebe, Heyer, Vincent, Fournier, Marjorie, Page, Adeline, Robert, Isabelle, Reina-San-Martin, Bernardo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832931/ https://www.ncbi.nlm.nih.gov/pubmed/24145512 http://dx.doi.org/10.1084/jem.20130166 |
Ejemplares similares
-
A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination
por: Enervald, Elin, et al.
Publicado: (2013) -
Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination
por: Jeevan-Raj, Beena Patricia, et al.
Publicado: (2011) -
Human PMS2 deficiency is associated with impaired immunoglobulin class switch recombination
por: Péron, Sophie, et al.
Publicado: (2008) -
Parp3 Negatively Regulates Immunoglobulin Class Switch Recombination
por: Robert, Isabelle, et al.
Publicado: (2015) -
Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination
por: Thomas-Claudepierre, Anne-Sophie, et al.
Publicado: (2016)