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Transcriptional Regulation of Δ6-Desaturase by Peroxisome Proliferative-Activated Receptor δ Agonist in Human Pancreatic Cancer Cells: Role of MEK/ERK1/2 Pathway
The Δ6-desaturase (Δ6D), also known as fatty acid desaturase 2, is a regulatory enzyme in de novo fatty acid synthesis, which has been linked to obesity and diabetes. The aim of the present study was to investigate the effect of peroxisome proliferative-activated receptor δ (PPARδ) agonist and MEK/E...
Autores principales: | Darabi, Maryam, Byagowi, Shima, Fayezi, Shabnam, Darabi, Masoud, Mirshahvaladi, Shahab, Sahmani, Mehdi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832962/ https://www.ncbi.nlm.nih.gov/pubmed/24294133 http://dx.doi.org/10.1155/2013/607524 |
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