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Intranuclear Crosstalk between Extracellular Regulated Kinase1/2 and Signal Transducer and Activator of Transcription 3 Regulates JEG-3 Choriocarcinoma Cell Invasion and Proliferation

Invasiveness of trophoblast and choriocarcinoma cells is in part mediated via leukemia inhibitory factor- (LIF-) induced activation of signal transducer and activator of transcription 3 (STAT3). The regulation of STAT3 phosphorylation at its ser727 binding site, possible crosstalk with intracellular...

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Detalles Bibliográficos
Autores principales: Morales-Prieto, Diana M., Ospina-Prieto, Stephanie, Chaiwangyen, Wittaya, Weber, Maja, Hölters, Sebastian, Schleussner, Ekkehard, Fitzgerald, Justine S., Markert, Udo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833059/
https://www.ncbi.nlm.nih.gov/pubmed/24288470
http://dx.doi.org/10.1155/2013/259845