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Extensive Growth of an Anaplastic Meningioma

We present the case of a 30-year-old male patient with an almost complete destruction of the calvarial bone through an anaplastic meningioma diagnosed in line with dizziness. Neuroimaging revealed an extensive growing, contrast enhancing lesion expanding at the supra- and infratentorial convexity, i...

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Autores principales: Ahmeti, Hajrullah, Maslehaty, Homajoun, Petridis, Athanasios K., Doukas, Alexandros, Mahvash, Mehran, Barth, Harald, Mehdorn, H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833072/
https://www.ncbi.nlm.nih.gov/pubmed/24288634
http://dx.doi.org/10.1155/2013/527184
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author Ahmeti, Hajrullah
Maslehaty, Homajoun
Petridis, Athanasios K.
Doukas, Alexandros
Mahvash, Mehran
Barth, Harald
Mehdorn, H. M.
author_facet Ahmeti, Hajrullah
Maslehaty, Homajoun
Petridis, Athanasios K.
Doukas, Alexandros
Mahvash, Mehran
Barth, Harald
Mehdorn, H. M.
author_sort Ahmeti, Hajrullah
collection PubMed
description We present the case of a 30-year-old male patient with an almost complete destruction of the calvarial bone through an anaplastic meningioma diagnosed in line with dizziness. Neuroimaging revealed an extensive growing, contrast enhancing lesion expanding at the supra- and infratentorial convexity, infiltrating and destroying large parts of the skull, and infiltrating the skin. Due to progressive ataxia and dysarthria with proven tumor growth in the posterior fossa in the continuing course, parts of the tumor were resected. A surgical procedure with the aim of complete tumor resection in a curative manner was not possible. Six months after the first operation, due to a new tumor progression, most extensive tumor resection was performed. Due to the aggressive and destructive growth with a high rate of recurrence and tendency of metastases, anaplastic meningiomas can be termed as malignant tumors. The extrinsic growth masks the tumor until they reach a size, which makes these tumors almost unresectable. In the best case scenarios, the five-year survival is about 50%. With the presented case, we would like to show the aggressive behavior of anaplastic meningiomas in a very illustrative way. Chemotherapy, radiotherapy, and surgery reach their limits in this tumor entity.
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spelling pubmed-38330722013-11-28 Extensive Growth of an Anaplastic Meningioma Ahmeti, Hajrullah Maslehaty, Homajoun Petridis, Athanasios K. Doukas, Alexandros Mahvash, Mehran Barth, Harald Mehdorn, H. M. Case Rep Neurol Med Case Report We present the case of a 30-year-old male patient with an almost complete destruction of the calvarial bone through an anaplastic meningioma diagnosed in line with dizziness. Neuroimaging revealed an extensive growing, contrast enhancing lesion expanding at the supra- and infratentorial convexity, infiltrating and destroying large parts of the skull, and infiltrating the skin. Due to progressive ataxia and dysarthria with proven tumor growth in the posterior fossa in the continuing course, parts of the tumor were resected. A surgical procedure with the aim of complete tumor resection in a curative manner was not possible. Six months after the first operation, due to a new tumor progression, most extensive tumor resection was performed. Due to the aggressive and destructive growth with a high rate of recurrence and tendency of metastases, anaplastic meningiomas can be termed as malignant tumors. The extrinsic growth masks the tumor until they reach a size, which makes these tumors almost unresectable. In the best case scenarios, the five-year survival is about 50%. With the presented case, we would like to show the aggressive behavior of anaplastic meningiomas in a very illustrative way. Chemotherapy, radiotherapy, and surgery reach their limits in this tumor entity. Hindawi Publishing Corporation 2013 2013-10-31 /pmc/articles/PMC3833072/ /pubmed/24288634 http://dx.doi.org/10.1155/2013/527184 Text en Copyright © 2013 Hajrullah Ahmeti et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ahmeti, Hajrullah
Maslehaty, Homajoun
Petridis, Athanasios K.
Doukas, Alexandros
Mahvash, Mehran
Barth, Harald
Mehdorn, H. M.
Extensive Growth of an Anaplastic Meningioma
title Extensive Growth of an Anaplastic Meningioma
title_full Extensive Growth of an Anaplastic Meningioma
title_fullStr Extensive Growth of an Anaplastic Meningioma
title_full_unstemmed Extensive Growth of an Anaplastic Meningioma
title_short Extensive Growth of an Anaplastic Meningioma
title_sort extensive growth of an anaplastic meningioma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833072/
https://www.ncbi.nlm.nih.gov/pubmed/24288634
http://dx.doi.org/10.1155/2013/527184
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