Fulvestrant induces resistance by modulating GPER and CDK6 expression: implication of methyltransferases, deacetylases and the hSWI/SNF chromatin remodelling complex

BACKGROUND: Breast cancer is the leading cause of cancer death in women living in the western hemisphere. Despite major advances in first-line endocrine therapy of advanced oestrogen receptor (ER)-positive breast cancer, the frequent recurrence of resistant cancer cells represents a serious obstacle...

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Detalles Bibliográficos
Autores principales: Giessrigl, B, Schmidt, W M, Kalipciyan, M, Jeitler, M, Bilban, M, Gollinger, M, Krieger, S, Jäger, W, Mader, R M, Krupitza, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833203/
https://www.ncbi.nlm.nih.gov/pubmed/24169358
http://dx.doi.org/10.1038/bjc.2013.583

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