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Alternative Splice Variants, a New Class of Protein Cancer Biomarker Candidates: Findings in Pancreatic Cancer and Breast Cancer with Systems Biology Implications

Alternative splicing plays an important role in protein diversity without increasing genome size. Earlier thought to be uncommon, splicing appears to affect the majority of genes. Alternative splice variants have been detected at the mRNA level in many diseases. We have designed and demonstrated a d...

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Detalles Bibliográficos
Autores principales: Omenn, Gilbert S., Yocum, Anastasia K., Menon, Rajasree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833236/
https://www.ncbi.nlm.nih.gov/pubmed/20534909
http://dx.doi.org/10.3233/DMA-2010-0702