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P2X7 Gene Polymorphisms and Risk Assessment for Pulmonary Tuberculosis in Asian Indians

Objective: Pulmonary tuberculosis (PTB) is a leading cause of morbidity and mortality. Macrophages play an important role in the immunopathogenesis of tuberculosis. Extracellular ATP induces macrophage bactericidal activity through activation of the purinergic P2X7 receptor. This case- control study...

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Detalles Bibliográficos
Autores principales: Sambasivan, Venkatasubramanian, Murthy, Kolluri Janaki Rama, Reddy, Ravindra, Vijayalakshimi, Valluri, Hasan, Qurratulain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833339/
https://www.ncbi.nlm.nih.gov/pubmed/20164546
http://dx.doi.org/10.3233/DMA-2010-0682