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In Support of Clinical Case Reports: A System of Causality Assessment
The usefulness of clinical research depends on an assessment of causality. This assessment determines what constitutes clinical evidence. Case reports are an example of evidence that is frequently overlooked because it is believed they cannot address causal links between treatment and outcomes. This...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Global Advances in Health and Medicine
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833527/ https://www.ncbi.nlm.nih.gov/pubmed/24416665 http://dx.doi.org/10.7453/gahmj.2012.061 |
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author | Kiene, Helmut Hamre, Harald J. Kienle, Gunver S. |
author_facet | Kiene, Helmut Hamre, Harald J. Kienle, Gunver S. |
author_sort | Kiene, Helmut |
collection | PubMed |
description | The usefulness of clinical research depends on an assessment of causality. This assessment determines what constitutes clinical evidence. Case reports are an example of evidence that is frequently overlooked because it is believed they cannot address causal links between treatment and outcomes. This may be a mistake. Clarity on the topic of causality and its assessment will be of benefit for researchers and clinicians. This article outlines an overall system of causality and causality assessment. The system proposed involves two dimensions: horizontal and vertical; each of these dimensions consists of three different types of causality and three corresponding types of causality assessment. Included in this system are diverse forms of case causality illustrated with examples from everyday life and clinical medicine. Assessing case causality can complement conventional clinical research in an era of personalized medicine. |
format | Online Article Text |
id | pubmed-3833527 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Global Advances in Health and Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-38335272014-03-01 In Support of Clinical Case Reports: A System of Causality Assessment Kiene, Helmut Hamre, Harald J. Kienle, Gunver S. Glob Adv Health Med Methodology Review The usefulness of clinical research depends on an assessment of causality. This assessment determines what constitutes clinical evidence. Case reports are an example of evidence that is frequently overlooked because it is believed they cannot address causal links between treatment and outcomes. This may be a mistake. Clarity on the topic of causality and its assessment will be of benefit for researchers and clinicians. This article outlines an overall system of causality and causality assessment. The system proposed involves two dimensions: horizontal and vertical; each of these dimensions consists of three different types of causality and three corresponding types of causality assessment. Included in this system are diverse forms of case causality illustrated with examples from everyday life and clinical medicine. Assessing case causality can complement conventional clinical research in an era of personalized medicine. Global Advances in Health and Medicine 2013-03 2013-03-01 /pmc/articles/PMC3833527/ /pubmed/24416665 http://dx.doi.org/10.7453/gahmj.2012.061 Text en © 2013 GAHM LLC. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial- No Derivative 3.0 License, which permits rights to copy, distribute and transmit the work for noncommercial purposes only, provided the original work is properly cited. |
spellingShingle | Methodology Review Kiene, Helmut Hamre, Harald J. Kienle, Gunver S. In Support of Clinical Case Reports: A System of Causality Assessment |
title | In Support of Clinical Case Reports: A System of Causality Assessment |
title_full | In Support of Clinical Case Reports: A System of Causality Assessment |
title_fullStr | In Support of Clinical Case Reports: A System of Causality Assessment |
title_full_unstemmed | In Support of Clinical Case Reports: A System of Causality Assessment |
title_short | In Support of Clinical Case Reports: A System of Causality Assessment |
title_sort | in support of clinical case reports: a system of causality assessment |
topic | Methodology Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833527/ https://www.ncbi.nlm.nih.gov/pubmed/24416665 http://dx.doi.org/10.7453/gahmj.2012.061 |
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