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Profile of panobinostat and its potential for treatment in solid tumors: an update
The histone deacetylase (HDAC) inhibitors have emerged as novel therapies for cancer. Panobinostat (LBH 589, Novartis Pharmaceuticals) is a pan-deacetylase inhibitor that is being evaluated in both intravenous and oral formulations across multiple tumor types. Comparable to the other HDACs, panobino...
Autores principales: | Anne, Madhurima, Sammartino, Daniel, Barginear, Myra F, Budman, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833618/ https://www.ncbi.nlm.nih.gov/pubmed/24265556 http://dx.doi.org/10.2147/OTT.S30773 |
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