A physiologically-based flow network model for hepatic drug elimination II: variable lattice lobule models

We extend a physiologically-based lattice model for the transport and metabolism of drugs in the liver lobule (liver functional unit) to consider structural and spatial variability. We compare predicted drug concentration levels observed exiting the lobule with their detailed distribution inside the...

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Detalles Bibliográficos
Autores principales: Rezania, Vahid, Marsh, Rebeccah, Coombe, Dennis, Tuszynski, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833673/
https://www.ncbi.nlm.nih.gov/pubmed/24007357
http://dx.doi.org/10.1186/1742-4682-10-53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833673/
https://www.ncbi.nlm.nih.gov/pubmed/24007357
http://dx.doi.org/10.1186/1742-4682-10-53

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