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A physiologically-based flow network model for hepatic drug elimination II: variable lattice lobule models
We extend a physiologically-based lattice model for the transport and metabolism of drugs in the liver lobule (liver functional unit) to consider structural and spatial variability. We compare predicted drug concentration levels observed exiting the lobule with their detailed distribution inside the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833673/ https://www.ncbi.nlm.nih.gov/pubmed/24007357 http://dx.doi.org/10.1186/1742-4682-10-53 |