Site-Directed Spin Labeling Reveals Pentameric Ligand-Gated Ion Channel Gating Motions

Pentameric ligand-gated ion channels (pLGICs) are neurotransmitter-activated receptors that mediate fast synaptic transmission. In pLGICs, binding of agonist to the extracellular domain triggers a structural rearrangement that leads to the opening of an ion-conducting pore in the transmembrane domai...

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Detalles Bibliográficos
Autores principales: Dellisanti, Cosma D., Ghosh, Borna, Hanson, Susan M., Raspanti, James M., Grant, Valerie A., Diarra, Gaoussou M., Schuh, Abby M., Satyshur, Kenneth, Klug, Candice S., Czajkowski, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833874/
https://www.ncbi.nlm.nih.gov/pubmed/24260024
http://dx.doi.org/10.1371/journal.pbio.1001714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833874/
https://www.ncbi.nlm.nih.gov/pubmed/24260024
http://dx.doi.org/10.1371/journal.pbio.1001714

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