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PX-12-induced HeLa cell death is associated with oxidative stress and GSH depletion
PX-12, as an inhibitor of thioredoxin (Trx), has antitumor activity. However, little is known about the toxicological effect of PX-12 on cervical cancer cells. In the present study, the growth inhibitory effects of PX-12 on HeLa cervical cancer cells in association with reactive oxygen species (ROS)...
Autores principales: | SHIN, HYE RIM, YOU, BO RA, PARK, WOO HYUN |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833989/ https://www.ncbi.nlm.nih.gov/pubmed/24260080 http://dx.doi.org/10.3892/ol.2013.1637 |
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