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Targeting of Histone Deacetylases to Reactivate Tumour Suppressor Genes and Its Therapeutic Potential in a Human Cervical Cancer Xenograft Model
Aberrant histone acetylation plays an essential role in the neoplastic process via the epigenetic silencing of tumour suppressor genes (TSGs); therefore, the inhibition of histone deacetylases (HDAC) has become a promising target in cancer therapeutics. To investigate the correlation of histone acet...
Autores principales: | Feng, Dingqing, Wu, Jiao, Tian, Yuan, Zhou, Hu, Zhou, Ying, Hu, Weiping, Zhao, Weidong, Wei, Haiming, Ling, Bin, Ma, Chunhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834007/ https://www.ncbi.nlm.nih.gov/pubmed/24260446 http://dx.doi.org/10.1371/journal.pone.0080657 |
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