High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy()

Three-dimensional (3D) structure determination by single particle electron cryomicroscopy (cryoEM) involves the calculation of an initial 3D model, followed by extensive iterative improvement of the orientation determination of the individual particle images and the resulting 3D map. Because there i...

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Detalles Bibliográficos
Autores principales: Chen, Shaoxia, McMullan, Greg, Faruqi, Abdul R., Murshudov, Garib N., Short, Judith M., Scheres, Sjors H.W., Henderson, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834153/
https://www.ncbi.nlm.nih.gov/pubmed/23872039
http://dx.doi.org/10.1016/j.ultramic.2013.06.004

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