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Attenuation of VEGFR-2 Expression by sFlt-1 and Low Oxygen in Human Placenta
Vascular endothelial growth factor receptor 2 (VEGFR-2), the primary receptor for VEGF, is crucial for normal endothelial function. sFlt-1, a truncated and soluble form of VEGFR-1 which binds and inhibits VEGF, is increased in preeclampsia and is positively regulated by low oxygen. Here, we investig...
Autores principales: | Nevo, Ori, Lee, Dennis K., Caniggia, Isabella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834253/ https://www.ncbi.nlm.nih.gov/pubmed/24260556 http://dx.doi.org/10.1371/journal.pone.0081176 |
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