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Spironolactone Attenuates Bleomycin-Induced Pulmonary Injury Partially via Modulating Mononuclear Phagocyte Phenotype Switching in Circulating and Alveolar Compartments

BACKGROUND: Recent experimental studies provide evidence indicating that manipulation of the mononuclear phagocyte phenotype could be a feasible approach to alter the severity and persistence of pulmonary injury and fibrosis. Mineralocorticoid receptor (MR) has been reported as a target to regulate...

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Detalles Bibliográficos
Autores principales: Ji, Wen-Jie, Ma, Yong-Qiang, Zhou, Xin, Zhang, Yi-Dan, Lu, Rui-Yi, Guo, Zhao-Zeng, Sun, Hai-Ying, Hu, Dao-Chuan, Yang, Guo-Hong, Li, Yu-Ming, Wei, Lu-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834272/
https://www.ncbi.nlm.nih.gov/pubmed/24260540
http://dx.doi.org/10.1371/journal.pone.0081090