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A New Way in Deciding NOAEL Based on the Findings from GLP-Toxicity Test

The FDA guidance focuses on the use of the NOAEL to establish the maximum recommended starting dose. The majority of NOAEL has been described inaccurately or incompletely in final reports for 90-days repeated dose toxicity test based on GLP (good laboratory practice) regulation. This is the most ser...

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Detalles Bibliográficos
Autores principales: Park, Yeong-Chul, Cho, Myung-Haing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Toxicology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834376/
https://www.ncbi.nlm.nih.gov/pubmed/24278562
http://dx.doi.org/10.5487/TR.2011.27.3.133