Cargando…
Determination of Optimal Toxic Concentration and Accumulation of Cadmium in Broiler Chicks
Cadmium is considered one of the most toxic, non biodegradable heavy metal for the human and animals. The purpose of the present study was to investigate the changes in biochemical parameters of blood and accumulation of cadmium in various tissue caused by various levels of dietary cadmium chloride...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Toxicology
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834379/ https://www.ncbi.nlm.nih.gov/pubmed/24278564 http://dx.doi.org/10.5487/TR.2011.27.3.143 |
_version_ | 1782291975809007616 |
---|---|
author | Subhan, Fazli Khan, Ayaz Wahid, Fazli Shehzad, Adeeb Jan, Amin Ullah |
author_facet | Subhan, Fazli Khan, Ayaz Wahid, Fazli Shehzad, Adeeb Jan, Amin Ullah |
author_sort | Subhan, Fazli |
collection | PubMed |
description | Cadmium is considered one of the most toxic, non biodegradable heavy metal for the human and animals. The purpose of the present study was to investigate the changes in biochemical parameters of blood and accumulation of cadmium in various tissue caused by various levels of dietary cadmium chloride (CdCl(2)) in broiler chicks. CdCl(2) was administered through drinking water to broiler chicks. In spectral analysis, CdCl(2) treatment caused a significant increase in Glutamate pyruvate transaminase (GPT), creatinine and uric acid levels in all treated groups. Intriguingly, the GPT, creatinine, and uric acid levels were significantly higher at 75 mg/kg as compared to the groups treated with high doses (100, 125 and 150 mg/kg) of CdCl(2). Atomic Absorption Spectrophotometer (AAS) was used for the determination of Cd accumulation in kidney, liver and Breast muscles. AAS analysis revealed that Cd accumulation is increased in breast muscles as compared to liver and kidney at higher doses of Cd than 75 mg/kg. |
format | Online Article Text |
id | pubmed-3834379 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | The Korean Society of Toxicology |
record_format | MEDLINE/PubMed |
spelling | pubmed-38343792013-11-25 Determination of Optimal Toxic Concentration and Accumulation of Cadmium in Broiler Chicks Subhan, Fazli Khan, Ayaz Wahid, Fazli Shehzad, Adeeb Jan, Amin Ullah Toxicol Res Articles Cadmium is considered one of the most toxic, non biodegradable heavy metal for the human and animals. The purpose of the present study was to investigate the changes in biochemical parameters of blood and accumulation of cadmium in various tissue caused by various levels of dietary cadmium chloride (CdCl(2)) in broiler chicks. CdCl(2) was administered through drinking water to broiler chicks. In spectral analysis, CdCl(2) treatment caused a significant increase in Glutamate pyruvate transaminase (GPT), creatinine and uric acid levels in all treated groups. Intriguingly, the GPT, creatinine, and uric acid levels were significantly higher at 75 mg/kg as compared to the groups treated with high doses (100, 125 and 150 mg/kg) of CdCl(2). Atomic Absorption Spectrophotometer (AAS) was used for the determination of Cd accumulation in kidney, liver and Breast muscles. AAS analysis revealed that Cd accumulation is increased in breast muscles as compared to liver and kidney at higher doses of Cd than 75 mg/kg. The Korean Society of Toxicology 2011-09 /pmc/articles/PMC3834379/ /pubmed/24278564 http://dx.doi.org/10.5487/TR.2011.27.3.143 Text en Copyright ©2011, The Korean Society of Toxicology |
spellingShingle | Articles Subhan, Fazli Khan, Ayaz Wahid, Fazli Shehzad, Adeeb Jan, Amin Ullah Determination of Optimal Toxic Concentration and Accumulation of Cadmium in Broiler Chicks |
title | Determination of Optimal Toxic Concentration and Accumulation of Cadmium in Broiler Chicks |
title_full | Determination of Optimal Toxic Concentration and Accumulation of Cadmium in Broiler Chicks |
title_fullStr | Determination of Optimal Toxic Concentration and Accumulation of Cadmium in Broiler Chicks |
title_full_unstemmed | Determination of Optimal Toxic Concentration and Accumulation of Cadmium in Broiler Chicks |
title_short | Determination of Optimal Toxic Concentration and Accumulation of Cadmium in Broiler Chicks |
title_sort | determination of optimal toxic concentration and accumulation of cadmium in broiler chicks |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834379/ https://www.ncbi.nlm.nih.gov/pubmed/24278564 http://dx.doi.org/10.5487/TR.2011.27.3.143 |
work_keys_str_mv | AT subhanfazli determinationofoptimaltoxicconcentrationandaccumulationofcadmiuminbroilerchicks AT khanayaz determinationofoptimaltoxicconcentrationandaccumulationofcadmiuminbroilerchicks AT wahidfazli determinationofoptimaltoxicconcentrationandaccumulationofcadmiuminbroilerchicks AT shehzadadeeb determinationofoptimaltoxicconcentrationandaccumulationofcadmiuminbroilerchicks AT janaminullah determinationofoptimaltoxicconcentrationandaccumulationofcadmiuminbroilerchicks |