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Risk Assessment Principle for Engineered Nanotechnology in Food and Drug

While the ability to develop nanomaterials and incorporate them into products is advancing rapidly worldwide, understanding of the potential health safety effects of nanomaterials has proceeded at a much slower pace. Since 2008, Korea Food and Drug Administration (KFDA) started an investigation to p...

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Autores principales: Hwang, Myungsil, Lee, Eun Ji, Kweon, Se Young, Park, Mi Sun, Jeong, Ji Yoon, Um, Jun Ho, Kim, Sun Ah, Han, Bum Suk, Lee, Kwang Ho, Yoon, Hae Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Toxicology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834411/
https://www.ncbi.nlm.nih.gov/pubmed/24278592
http://dx.doi.org/10.5487/TR.2012.28.2.073
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author Hwang, Myungsil
Lee, Eun Ji
Kweon, Se Young
Park, Mi Sun
Jeong, Ji Yoon
Um, Jun Ho
Kim, Sun Ah
Han, Bum Suk
Lee, Kwang Ho
Yoon, Hae Jung
author_facet Hwang, Myungsil
Lee, Eun Ji
Kweon, Se Young
Park, Mi Sun
Jeong, Ji Yoon
Um, Jun Ho
Kim, Sun Ah
Han, Bum Suk
Lee, Kwang Ho
Yoon, Hae Jung
author_sort Hwang, Myungsil
collection PubMed
description While the ability to develop nanomaterials and incorporate them into products is advancing rapidly worldwide, understanding of the potential health safety effects of nanomaterials has proceeded at a much slower pace. Since 2008, Korea Food and Drug Administration (KFDA) started an investigation to prepare “Strategic Action Plan” to evaluate safety and nano risk management associated with foods, drugs, medical devices and cosmetics using nano-scale materials. Although there are some studies related to potential risk of nanomaterials, physical-chemical characterization of nanomaterials is not clear yet and these do not offer enough information due to their limitations. Their uncertainties make it impossible to determine whether nanomaterials are actually hazardous to human. According to the above mention, we have some problems to conduct the human exposure risk assessment currently. On the other hand, uncertainty about safety may lead to polarized public debate and to businesses unwillingness for further nanotechnology investigation. Therefore, the criteria and methods to assess possible adverse effects of nanomaterials have been vigorously taken into consideration by many international organizations: the World Health Organization, the Organization for Economic and Commercial Development and the European Commission. The object of this study was to develop risk assessment principles for safety management of future nanoproducts and also to identify areas of research to strengthen risk assessment for nanomaterials. The research roadmaps which were proposed in this study will be helpful to fill up the current gaps in knowledge relevant nano risk assessment.
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spelling pubmed-38344112013-11-25 Risk Assessment Principle for Engineered Nanotechnology in Food and Drug Hwang, Myungsil Lee, Eun Ji Kweon, Se Young Park, Mi Sun Jeong, Ji Yoon Um, Jun Ho Kim, Sun Ah Han, Bum Suk Lee, Kwang Ho Yoon, Hae Jung Toxicol Res Articles While the ability to develop nanomaterials and incorporate them into products is advancing rapidly worldwide, understanding of the potential health safety effects of nanomaterials has proceeded at a much slower pace. Since 2008, Korea Food and Drug Administration (KFDA) started an investigation to prepare “Strategic Action Plan” to evaluate safety and nano risk management associated with foods, drugs, medical devices and cosmetics using nano-scale materials. Although there are some studies related to potential risk of nanomaterials, physical-chemical characterization of nanomaterials is not clear yet and these do not offer enough information due to their limitations. Their uncertainties make it impossible to determine whether nanomaterials are actually hazardous to human. According to the above mention, we have some problems to conduct the human exposure risk assessment currently. On the other hand, uncertainty about safety may lead to polarized public debate and to businesses unwillingness for further nanotechnology investigation. Therefore, the criteria and methods to assess possible adverse effects of nanomaterials have been vigorously taken into consideration by many international organizations: the World Health Organization, the Organization for Economic and Commercial Development and the European Commission. The object of this study was to develop risk assessment principles for safety management of future nanoproducts and also to identify areas of research to strengthen risk assessment for nanomaterials. The research roadmaps which were proposed in this study will be helpful to fill up the current gaps in knowledge relevant nano risk assessment. The Korean Society of Toxicology 2012-06 /pmc/articles/PMC3834411/ /pubmed/24278592 http://dx.doi.org/10.5487/TR.2012.28.2.073 Text en Copyright ©2012, The Korean Society of Toxicology
spellingShingle Articles
Hwang, Myungsil
Lee, Eun Ji
Kweon, Se Young
Park, Mi Sun
Jeong, Ji Yoon
Um, Jun Ho
Kim, Sun Ah
Han, Bum Suk
Lee, Kwang Ho
Yoon, Hae Jung
Risk Assessment Principle for Engineered Nanotechnology in Food and Drug
title Risk Assessment Principle for Engineered Nanotechnology in Food and Drug
title_full Risk Assessment Principle for Engineered Nanotechnology in Food and Drug
title_fullStr Risk Assessment Principle for Engineered Nanotechnology in Food and Drug
title_full_unstemmed Risk Assessment Principle for Engineered Nanotechnology in Food and Drug
title_short Risk Assessment Principle for Engineered Nanotechnology in Food and Drug
title_sort risk assessment principle for engineered nanotechnology in food and drug
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834411/
https://www.ncbi.nlm.nih.gov/pubmed/24278592
http://dx.doi.org/10.5487/TR.2012.28.2.073
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