Cargando…

Single-Dose Oral Toxicity of Fermented Scutellariae Radix Extract in Rats and Dogs

The aim of this study was to investigate the acute oral toxicity of fermented Scutellariae Radix (JKTMHGu- 100) in rats and dogs. JKTM-HGu-100 was orally administered at a dose of 2,000 mg/kg in Sprague-Dawley rats. An escalating single-dose oral toxicity test in beagle dogs was performed at doses o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Myoung-Seok, Ham, Seoung-Ho, Kim, Jun-Ho, Shin, Ji-Eun, Oh, Jin, Kim, Tae-Won, Yun, Hyo-In, Lim, Jong-Hwan, Jang, Beom-Su, Cho, Jung-Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Toxicology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834431/ https://www.ncbi.nlm.nih.gov/pubmed/24278619 http://dx.doi.org/10.5487/TR.2012.28.4.263

Ejemplares similares

Radix Scutellariae — Huangqin
por: Wagner, Hildebert, et al.
Publicado: (2011)

Wogonin, a plant flavone from Scutellariae radix, attenuated ovalbumin-induced airway inflammation in mouse model of asthma via the suppression of IL-4/STAT6 signaling
por: Ryu, Eun Kyung, et al.
Publicado: (2015)

Complexity of active medicinal ingredients in radix scutellariae with sodium hydrosulfite exposure
por: Shen, Ying, et al.
Publicado: (2020)

Advances in Anti-Cancer Activities of Flavonoids in Scutellariae radix: Perspectives on Mechanism
por: Gu, Yiqing, et al.
Publicado: (2022)

Anti-Inflammatory Effect of Combination of Scutellariae Radix and Liriopis Tuber Water Extract
por: So, Mi-Hye, et al.
Publicado: (2015)

Sodium dithionite-enhanced quality of radix scutellariae through modification of secondary metabolism
por: Huimin, Guo, et al.
Publicado: (2016)

Network Pharmacology-Based Study on the Mechanism of Scutellariae Radix for Hepatocellular Carcinoma Treatment
por: Wang, Qian, et al.
Publicado: (2020)

Development of an amoxicillin-radix scutellaria extract formulation and evaluation of its pharmacokinetics in pigs
por: Yi, Dandan, et al.
Publicado: (2023)

Synergistic Effect of Bupleuri Radix and Scutellariae Radix on Adipogenesis and AMP-Activated Protein Kinase: A Network Pharmacological Approach
por: Lee, Jueun, et al.
Publicado: (2018)

Network-based pharmacology and molecular docking exploring the “Bupleuri Radix-Scutellariae Radix” mechanism of action in the viral hepatitis B treatment
por: Long, Piao, et al.
Publicado: (2022)

Herbal formula, Scutellariae radix and Rhei rhizoma attenuate dimethylnitrosamine-induced liver fibrosis in a rat model
por: Pan, Tai-Long, et al.
Publicado: (2015)

Elucidation of the Anti-Inflammatory Mechanisms of Bupleuri and Scutellariae Radix Using System Pharmacological Analyses
por: Shen, Xia, et al.
Publicado: (2017)

Mechanism of Radix Scutellariae in the treatment of influenza A based on network pharmacology and molecular docking
por: Li, Qing, et al.
Publicado: (2022)

The Chitosan-Based System with Scutellariae baicalensis radix Extract for the Local Treatment of Vaginal Infections
por: Chanaj-Kaczmarek, Justyna, et al.
Publicado: (2022)

To study the mechanism of Scutellariae Radix and Astragaloside in the treatment of lung cancer based on network pharmacology
por: Wang, Zijuan, et al.
Publicado: (2022)

Comparative Study of the Flavonoid Content in Radix Scutellaria from Different Cultivation Areas in China
por: Zheng, Yiying, et al.
Publicado: (2023)

Fermented Soy Products: Beneficial Potential in Neurodegenerative Diseases
por: Jang, Chan Ho, et al.
Publicado: (2021)

Mouse Single Oral Dose Toxicity Test of Bupleuri Radix Aqueous Extracts
por: Kim, Kyung-Hu, et al.
Publicado: (2012)

H(2)O(2) Improves Quality of Radix scutellariae Through Anti-oxidant Effect
por: Qi, Song, et al.
Publicado: (2016)

An activity-integrated strategy of the identification, screening and determination of potential neuraminidase inhibitors from Radix Scutellariae
por: Liu, Wei, et al.
Publicado: (2017)

Rapid determination of baicalin and total baicalein content in Scutellariae radix by ATR-IR and NIR spectroscopy
por: Navarro Escamilla, M., et al.
Publicado: (2013)

Wine-processed radix scutellariae alleviates ARDS by regulating tryptophan metabolism through gut microbiota
por: Hu, Tingting, et al.
Publicado: (2023)

Protective effects of Scutellariae Radix Carbonisata-derived carbon dots on blood-heat and hemorrhage rats
por: Zhang, Meiling, et al.
Publicado: (2023)

Quantification of propionic acid from Scutellaria baicalensis roots
por: Son, Eunjung, et al.
Publicado: (2017)

Acute and repeated toxicological study of Myelophil, an ethanol extract of a mixture of Astragali Radix and Salviae Miltiorrhizae Radix, in beagle dogs
por: Joung, Jin-Yong, et al.
Publicado: (2019)

Effects of Mixed Herbal Extracts from Parched Puerariae Radix, Gingered Magnoliae Cortex, Glycyrrhizae Radix and Euphorbiae Radix (KIOM-79) on Cardiac Ion Channels and Action Potentials
por: Park, Su Jung, et al.
Publicado: (2009)

Application of Scutellariae radix, Gardeniae fructus, and Probiotics to Prevent Salmonella enterica Serovar Choleraesuis Infection in Swine
por: Chang, Chiung-Hung, et al.
Publicado: (2013)

Flavones Isolated from Scutellariae radix Suppress Propionibacterium Acnes-Induced Cytokine Production In Vitro and In Vivo
por: Tsai, Po-Jung, et al.
Publicado: (2015)

Scutellariae Radix and Citri Reticulatae Pericarpium Mixture Regulate PPARγ/RXR Signaling in Reflux Esophagitis
por: Lee, Jin A., et al.
Publicado: (2022)

Comparative Pharmacokinetics of Baicalin, Wogonoside, Baicalein and Wogonin in Plasma after Oral Administration of Pure Baicalin, Radix Scutellariae and Scutellariae-Paeoniae Couple Extracts in Normal and Ulcerative Colitis Rats
por: Zhang, Zhen-Qiu, et al.
Publicado: (2013)

Synergistic inhibitory activity of Glycyrrhizae Radix and Rubi Fructus extracts on biofilm formation of Streptococcus mutans
por: Ham, Youngseok, et al.
Publicado: (2023)

Effect of Ampelopsis Radix on wound healing in scalded rats
por: Lee, Kyungjin, et al.
Publicado: (2015)

Antiosteoporosis Effect of Radix Scutellariae Extract on Density and Microstructure of Long Bones in Tail-Suspended Sprague-Dawley Rats
por: Li, Chen-Rui, et al.
Publicado: (2013)

Recurrent Drug-induced Liver Injury Caused by the Incidental Readministration of a Kampo Formula Containing Scutellariae Radix
por: Shimada, Yutaka, et al.
Publicado: (2018)

Development and Evaluation of Thermosensitive Hydrogels with Binary Mixture of Scutellariae baicalensis radix Extract and Chitosan for Periodontal Diseases Treatment
por: Chanaj-Kaczmarek, Justyna, et al.
Publicado: (2021)

Chitosan as a Functional Carrier for the Local Delivery Anti-Inflammatory Systems Containing Scutellariae baicalensis radix Extract
por: Paczkowska-Walendowska, Magdalena, et al.
Publicado: (2022)

Single Oral Dose Toxicity Test of Platycodin D, a Saponin from Platycodin Radix in Mice
por: Lee, Won-Ho, et al.
Publicado: (2011)

Single- and Repeat-dose Oral Toxicity Studies of Lithospermum erythrorhizon Extract in Dogs
por: Nam, Chunja, et al.
Publicado: (2015)

EST sequencing and gene expression profiling in Scutellaria baicalensis
por: Park, Nam Il, et al.
Publicado: (2014)

Extraction of Flavonoids from Scutellariae Radix using Ultrasound-Assisted Deep Eutectic Solvents and Evaluation of Their Anti-Inflammatory Activities
por: Hao, Cui, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fa4qv8qbjq9v7g158kpneptlbl