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Susceptibility to ATP depletion of primary proximal tubular cell cultures derived from mice lacking either the α1 or the α2 isoform of the catalytic domain of AMPK

BACKGROUND: The purpose of this study was to determine whether AMPK influences the survival of primary cultures of mouse proximal tubular (MPT) cells subjected to metabolic stress. Previous studies, using an immortalized MPT cell line, suggest that AMPK is activated during metabolic stress, and amel...

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Detalles Bibliográficos
Autores principales: Lieberthal, Wilfred, Tang, Meiyi, Zhang, Leiqing, Viollet, Benoit, Patel, Vimal, Levine, Jerrold S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834531/
https://www.ncbi.nlm.nih.gov/pubmed/24228806
http://dx.doi.org/10.1186/1471-2369-14-251

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