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The influence of mTOR inhibitors on immunity and the relationship to post-transplant malignancy

The known role of mammalian target of rapamycin (mTOR) in the immune response has been rapidly evolving, from what was once thought to be a simple immunosuppressive antiproliferative effect on T cells to a very complex central role that serves to integrate multiple signals given to T cells, B cells...

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Detalles Bibliográficos
Autor principal: Geissler, Edward K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834556/
https://www.ncbi.nlm.nih.gov/pubmed/24565200
http://dx.doi.org/10.1186/2047-1440-2-S1-S2