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Recent Highlights of Metabolomics in Chinese Medicine Syndrome Research

Chinese medicine syndrome (CMS, “ZHENG” in Chinese) is an understanding of the regularity of disease occurrence and development as well as a certain stage of a comprehensive response of patients with body condition. However, because of the complexity of CMS and the limitation of present investigatio...

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Detalles Bibliográficos
Autores principales: Zhang, Ai-hua, Sun, Hui, Qiu, Shi, Wang, Xi-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834606/
https://www.ncbi.nlm.nih.gov/pubmed/24302964
http://dx.doi.org/10.1155/2013/402159
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author Zhang, Ai-hua
Sun, Hui
Qiu, Shi
Wang, Xi-jun
author_facet Zhang, Ai-hua
Sun, Hui
Qiu, Shi
Wang, Xi-jun
author_sort Zhang, Ai-hua
collection PubMed
description Chinese medicine syndrome (CMS, “ZHENG” in Chinese) is an understanding of the regularity of disease occurrence and development as well as a certain stage of a comprehensive response of patients with body condition. However, because of the complexity of CMS and the limitation of present investigation method, the research for deciphering the scientific basis and systematic features of CMS is difficult to go further. Metabolomics enables mapping of early biochemical changes in disease and hence provides an opportunity to develop predictive biomarkers. Moreover, its method and design resemble those of traditional Chinese medicine (TCM) which focuses on human disease via the integrity of close relationship between body and syndromes. In the systemic context, metabolomics has a convergence with TCM syndrome; therefore it could provide useful tools for exploring essence of CMS disease, facilitating personalized TCM, and will help to in-depth understand CMS. The integration of the metabolomics and CMS aspects will give promise to bridge the gap between Chinese and Western medicine and help catch the traditional features of CMS. In this paper, particular attention will be paid to the past successes in applications of robust metabolomic approaches to contribute to low-molecular-weight metabolites (biomarkers) discovery in CMS research and development.
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spelling pubmed-38346062013-12-03 Recent Highlights of Metabolomics in Chinese Medicine Syndrome Research Zhang, Ai-hua Sun, Hui Qiu, Shi Wang, Xi-jun Evid Based Complement Alternat Med Review Article Chinese medicine syndrome (CMS, “ZHENG” in Chinese) is an understanding of the regularity of disease occurrence and development as well as a certain stage of a comprehensive response of patients with body condition. However, because of the complexity of CMS and the limitation of present investigation method, the research for deciphering the scientific basis and systematic features of CMS is difficult to go further. Metabolomics enables mapping of early biochemical changes in disease and hence provides an opportunity to develop predictive biomarkers. Moreover, its method and design resemble those of traditional Chinese medicine (TCM) which focuses on human disease via the integrity of close relationship between body and syndromes. In the systemic context, metabolomics has a convergence with TCM syndrome; therefore it could provide useful tools for exploring essence of CMS disease, facilitating personalized TCM, and will help to in-depth understand CMS. The integration of the metabolomics and CMS aspects will give promise to bridge the gap between Chinese and Western medicine and help catch the traditional features of CMS. In this paper, particular attention will be paid to the past successes in applications of robust metabolomic approaches to contribute to low-molecular-weight metabolites (biomarkers) discovery in CMS research and development. Hindawi Publishing Corporation 2013 2013-11-04 /pmc/articles/PMC3834606/ /pubmed/24302964 http://dx.doi.org/10.1155/2013/402159 Text en Copyright © 2013 Ai-hua Zhang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Zhang, Ai-hua
Sun, Hui
Qiu, Shi
Wang, Xi-jun
Recent Highlights of Metabolomics in Chinese Medicine Syndrome Research
title Recent Highlights of Metabolomics in Chinese Medicine Syndrome Research
title_full Recent Highlights of Metabolomics in Chinese Medicine Syndrome Research
title_fullStr Recent Highlights of Metabolomics in Chinese Medicine Syndrome Research
title_full_unstemmed Recent Highlights of Metabolomics in Chinese Medicine Syndrome Research
title_short Recent Highlights of Metabolomics in Chinese Medicine Syndrome Research
title_sort recent highlights of metabolomics in chinese medicine syndrome research
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834606/
https://www.ncbi.nlm.nih.gov/pubmed/24302964
http://dx.doi.org/10.1155/2013/402159
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