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Mediator is an intrinsic component of the basal RNA polymerase II machinery in vivo

Mediator is a prominent multisubunit coactivator that functions as a bridge between gene-specific activators and the basal RNA polymerase (Pol) II initiation machinery. Here, we study the poorly documented role of Mediator in basal, or activator-independent, transcription in vivo. We show that Media...

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Detalles Bibliográficos
Autores principales: Lacombe, Thierry, Poh, Siew Lay, Barbey, Régine, Kuras, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834807/
https://www.ncbi.nlm.nih.gov/pubmed/23963697
http://dx.doi.org/10.1093/nar/gkt701