Cargando…
Mediator is an intrinsic component of the basal RNA polymerase II machinery in vivo
Mediator is a prominent multisubunit coactivator that functions as a bridge between gene-specific activators and the basal RNA polymerase (Pol) II initiation machinery. Here, we study the poorly documented role of Mediator in basal, or activator-independent, transcription in vivo. We show that Media...
Autores principales: | Lacombe, Thierry, Poh, Siew Lay, Barbey, Régine, Kuras, Laurent |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834807/ https://www.ncbi.nlm.nih.gov/pubmed/23963697 http://dx.doi.org/10.1093/nar/gkt701 |
Ejemplares similares
-
Transcriptional plasticity through differential assembly of a multiprotein activation complex
por: Cormier, Laëtitia, et al.
Publicado: (2010) -
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription
por: Steinbach, Nicole, et al.
Publicado: (2019) -
Che-1/AATF binds to RNA polymerase I machinery and sustains ribosomal RNA gene transcription
por: Sorino, Cristina, et al.
Publicado: (2020) -
Nuclear import of RNA polymerase II is coupled with nucleocytoplasmic shuttling of the RNA polymerase II-associated protein 2
por: Forget, Diane, et al.
Publicado: (2013) -
The global repressor FliZ antagonizes gene expression by σ(S)-containing RNA polymerase due to overlapping DNA binding specificity
por: Pesavento, Christina, et al.
Publicado: (2012)