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Opposing roles for 53BP1 during homologous recombination

Although DNA non-homologous end-joining repairs most DNA double-strand breaks (DSBs) in G2 phase, late repairing DSBs undergo resection and repair by homologous recombination (HR). Based on parallels to the situation in G1 cells, previous work has suggested that DSBs that undergo repair by HR predom...

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Detalles Bibliográficos
Autores principales:	Kakarougkas, Andreas, Ismail, Amani, Klement, Karolin, Goodarzi, Aaron A., Conrad, Sandro, Freire, Raimundo, Shibata, Atsushi, Lobrich, Markus, Jeggo, Penny A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834810/ https://www.ncbi.nlm.nih.gov/pubmed/23969417 http://dx.doi.org/10.1093/nar/gkt729

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