Crystal structures of B-DNA dodecamer containing the epigenetic modifications 5-hydroxymethylcytosine or 5-methylcytosine

5-Hydroxymethylcytosine (5-hmC) was recently identified as a relatively frequent base in eukaryotic genomes. Its physiological function is still unclear, but it is supposed to serve as an intermediate in DNA de novo demethylation. Using X-ray diffraction, we solved five structures of four variants o...

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Detalles Bibliográficos
Autores principales: Renciuk, Daniel, Blacque, Olivier, Vorlickova, Michaela, Spingler, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834816/
https://www.ncbi.nlm.nih.gov/pubmed/23963698
http://dx.doi.org/10.1093/nar/gkt738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834816/
https://www.ncbi.nlm.nih.gov/pubmed/23963698
http://dx.doi.org/10.1093/nar/gkt738

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