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Homology-mediated end-capping as a primary step of sister chromatid fusion in the breakage-fusion-bridge cycles
Breakage-fusion-bridge (BFB) cycle is a series of chromosome breaks and duplications that could lead to the increased copy number of a genomic segment (gene amplification). A critical step of BFB cycles leading to gene amplification is a palindromic fusion of sister chromatids following the rupture...
Autores principales: | Marotta, Michael, Chen, Xiongfong, Watanabe, Takaaki, Faber, Pieter W., Diede, Scott J., Tapscott, Stephen, Tubbs, Raymond, Kondratova, Anna, Stephens, Robert, Tanaka, Hisashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834830/ https://www.ncbi.nlm.nih.gov/pubmed/23975201 http://dx.doi.org/10.1093/nar/gkt762 |
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