Conformational transitions in human translin enable nucleic acid binding

Translin is a highly conserved RNA- and DNA-binding protein that plays essential roles in eukaryotic cells. Human translin functions as an octamer, but in the octameric crystallographic structure, the residues responsible for nucleic acid binding are not accessible. Moreover, electron microscopy dat...

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Detalles Bibliográficos
Autores principales: Pérez-Cano, Laura, Eliahoo, Elad, Lasker, Keren, Wolfson, Haim J., Glaser, Fabian, Manor, Haim, Bernadó, Pau, Fernández-Recio, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834833/
https://www.ncbi.nlm.nih.gov/pubmed/23980029
http://dx.doi.org/10.1093/nar/gkt765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834833/
https://www.ncbi.nlm.nih.gov/pubmed/23980029
http://dx.doi.org/10.1093/nar/gkt765

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