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Potent antitumor activity of the novel HSP90 inhibitors AUY922 and HSP990 in neuroendocrine carcinoid cells
The heat shock protein (HSP) 90 chaperone machine involved in numerous oncogenic signaling pathways is over-expressed in cancer cells and is currently being evaluated for anticancer therapy. Neuroendocrine tumors (NETs) of the gastroenteropancreatic (GEP) system comprise a heterogeneous group of tum...
Autores principales: | ZITZMANN, KATHRIN, AILER, GALINA, VLOTIDES, GEORGE, SPOETTL, GERALD, MAURER, JULIAN, GÖKE, BURKHARD, BEUSCHLEIN, FELIX, AUERNHAMMER, CHRISTOPH J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834873/ https://www.ncbi.nlm.nih.gov/pubmed/24100469 http://dx.doi.org/10.3892/ijo.2013.2130 |
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