Pharmacokinetic Evaluation of a DSPE-PEG(2000) Micellar Formulation of Ridaforolimus in Rat

The rapamycin analog, ridaforolimus, has demonstrated potent anti-proliferative effects in cancer treatment, and it currently is being evaluated in a range of clinical cancer studies. Ridaforolimus is an extremely lipophilic compound with limited aqueous solubility, which may benefit from formulatio...

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Detalles Bibliográficos
Autores principales: Remsberg, Connie M., Zhao, Yunqi, Takemoto, Jody K., Bertram, Rebecca M., Davies, Neal M., Forrest, Marcus Laird
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834941/
https://www.ncbi.nlm.nih.gov/pubmed/24300398
http://dx.doi.org/10.3390/pharmaceutics5010081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834941/
https://www.ncbi.nlm.nih.gov/pubmed/24300398
http://dx.doi.org/10.3390/pharmaceutics5010081

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