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Steroid Nanocrystals Prepared Using the Nano Spray Dryer B-90

The Nano Spray Dryer B-90 offers a new, simple, and alternative approach for the production of drug nanocrystals. In this study, the preparation of steroid nanocrystals using the Nano Spray Dryer B-90 was demonstrated. The particle size was controlled by selecting the mesh aperture size. Submicromet...

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Detalles Bibliográficos
Autores principales: Baba, Koichi, Nishida, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834944/
https://www.ncbi.nlm.nih.gov/pubmed/24300400
http://dx.doi.org/10.3390/pharmaceutics5010107
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author Baba, Koichi
Nishida, Kohji
author_facet Baba, Koichi
Nishida, Kohji
author_sort Baba, Koichi
collection PubMed
description The Nano Spray Dryer B-90 offers a new, simple, and alternative approach for the production of drug nanocrystals. In this study, the preparation of steroid nanocrystals using the Nano Spray Dryer B-90 was demonstrated. The particle size was controlled by selecting the mesh aperture size. Submicrometer steroid particles in powder form were successfully obtained. These nanoparticles were confirmed to have a crystal structure using powder X-ray diffraction pattern analysis. Since drug nanocrystals have recently been considered as a novel type of drug formulation for drug delivery systems, this study will be useful for nano-medical applications.
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spelling pubmed-38349442013-11-21 Steroid Nanocrystals Prepared Using the Nano Spray Dryer B-90 Baba, Koichi Nishida, Kohji Pharmaceutics Communication The Nano Spray Dryer B-90 offers a new, simple, and alternative approach for the production of drug nanocrystals. In this study, the preparation of steroid nanocrystals using the Nano Spray Dryer B-90 was demonstrated. The particle size was controlled by selecting the mesh aperture size. Submicrometer steroid particles in powder form were successfully obtained. These nanoparticles were confirmed to have a crystal structure using powder X-ray diffraction pattern analysis. Since drug nanocrystals have recently been considered as a novel type of drug formulation for drug delivery systems, this study will be useful for nano-medical applications. MDPI 2013-01-25 /pmc/articles/PMC3834944/ /pubmed/24300400 http://dx.doi.org/10.3390/pharmaceutics5010107 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Communication
Baba, Koichi
Nishida, Kohji
Steroid Nanocrystals Prepared Using the Nano Spray Dryer B-90
title Steroid Nanocrystals Prepared Using the Nano Spray Dryer B-90
title_full Steroid Nanocrystals Prepared Using the Nano Spray Dryer B-90
title_fullStr Steroid Nanocrystals Prepared Using the Nano Spray Dryer B-90
title_full_unstemmed Steroid Nanocrystals Prepared Using the Nano Spray Dryer B-90
title_short Steroid Nanocrystals Prepared Using the Nano Spray Dryer B-90
title_sort steroid nanocrystals prepared using the nano spray dryer b-90
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834944/
https://www.ncbi.nlm.nih.gov/pubmed/24300400
http://dx.doi.org/10.3390/pharmaceutics5010107
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