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Drug Adverse Event Detection in Health Plan Data Using the Gamma Poisson Shrinker and Comparison to the Tree-based Scan Statistic

Background: Drug adverse event (AE) signal detection using the Gamma Poisson Shrinker (GPS) is commonly applied in spontaneous reporting. AE signal detection using large observational health plan databases can expand medication safety surveillance. Methods: Using data from nine health plans, we cond...

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Detalles Bibliográficos
Autores principales: Brown, Jeffrey S., Petronis, Kenneth R., Bate, Andrew, Zhang, Fang, Dashevsky, Inna, Kulldorff, Martin, Avery, Taliser R., Davis, Robert L., Chan, K. Arnold, Andrade, Susan E., Boudreau, Denise, Gunter, Margaret J., Herrinton, Lisa, Pawloski, Pamala A., Raebel, Marsha A., Roblin, Douglas, Smith, David, Reynolds, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834945/
https://www.ncbi.nlm.nih.gov/pubmed/24300404
http://dx.doi.org/10.3390/pharmaceutics5010179