MicroRNAs in Head and Neck Squamous Cell Carcinoma (HNSCC) and Oral Squamous Cell Carcinoma (OSCC)

MicroRNAs (miRNAs) are small, noncoding RNAs which regulate cell differentiation, proliferation, development, cell cycle, and apoptosis. Expression profiling of miRNAs has been performed and the data show that some miRNAs are upregulated or downregulated in cancer. Several studies suggest that the e...

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Detalles Bibliográficos
Autores principales: Shiiba, Masashi, Uzawa, Katsuhiro, Tanzawa, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835097/
https://www.ncbi.nlm.nih.gov/pubmed/24281087
http://dx.doi.org/10.3390/cancers2020653
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author Shiiba, Masashi
Uzawa, Katsuhiro
Tanzawa, Hideki
author_facet Shiiba, Masashi
Uzawa, Katsuhiro
Tanzawa, Hideki
author_sort Shiiba, Masashi
collection PubMed
description MicroRNAs (miRNAs) are small, noncoding RNAs which regulate cell differentiation, proliferation, development, cell cycle, and apoptosis. Expression profiling of miRNAs has been performed and the data show that some miRNAs are upregulated or downregulated in cancer. Several studies suggest that the expression profiles of miRNAs are associated with clinical outcomes. However, the set of miRNAs with altered expressing differs depending on the type of cancer, suggesting that it is important to understand which miRNAs are related to which cancers. Therefore, this review aimed to discuss potentially crucial miRNAs in head and neck squamous cell carcinoma (HNSCC) and oral squamous cell carcinoma (OSCC).
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spelling pubmed-38350972013-11-21 MicroRNAs in Head and Neck Squamous Cell Carcinoma (HNSCC) and Oral Squamous Cell Carcinoma (OSCC) Shiiba, Masashi Uzawa, Katsuhiro Tanzawa, Hideki Cancers (Basel) Review MicroRNAs (miRNAs) are small, noncoding RNAs which regulate cell differentiation, proliferation, development, cell cycle, and apoptosis. Expression profiling of miRNAs has been performed and the data show that some miRNAs are upregulated or downregulated in cancer. Several studies suggest that the expression profiles of miRNAs are associated with clinical outcomes. However, the set of miRNAs with altered expressing differs depending on the type of cancer, suggesting that it is important to understand which miRNAs are related to which cancers. Therefore, this review aimed to discuss potentially crucial miRNAs in head and neck squamous cell carcinoma (HNSCC) and oral squamous cell carcinoma (OSCC). Molecular Diversity Preservation International 2010-04-21 /pmc/articles/PMC3835097/ /pubmed/24281087 http://dx.doi.org/10.3390/cancers2020653 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Shiiba, Masashi
Uzawa, Katsuhiro
Tanzawa, Hideki
MicroRNAs in Head and Neck Squamous Cell Carcinoma (HNSCC) and Oral Squamous Cell Carcinoma (OSCC)
title MicroRNAs in Head and Neck Squamous Cell Carcinoma (HNSCC) and Oral Squamous Cell Carcinoma (OSCC)
title_full MicroRNAs in Head and Neck Squamous Cell Carcinoma (HNSCC) and Oral Squamous Cell Carcinoma (OSCC)
title_fullStr MicroRNAs in Head and Neck Squamous Cell Carcinoma (HNSCC) and Oral Squamous Cell Carcinoma (OSCC)
title_full_unstemmed MicroRNAs in Head and Neck Squamous Cell Carcinoma (HNSCC) and Oral Squamous Cell Carcinoma (OSCC)
title_short MicroRNAs in Head and Neck Squamous Cell Carcinoma (HNSCC) and Oral Squamous Cell Carcinoma (OSCC)
title_sort micrornas in head and neck squamous cell carcinoma (hnscc) and oral squamous cell carcinoma (oscc)
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835097/
https://www.ncbi.nlm.nih.gov/pubmed/24281087
http://dx.doi.org/10.3390/cancers2020653
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