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Serum Tumor Markers in Pancreatic Cancer—Recent Discoveries
The low prevalence of pancreatic cancer remains an obstacle to the development of effective screening tools in an asymptomatic population. However, development of effective serologic markers still offers the potential for improvement of diagnostic capabilities, especially for subpopulations of patie...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835121/ https://www.ncbi.nlm.nih.gov/pubmed/24281109 http://dx.doi.org/10.3390/cancers2021107 |
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author | Rückert, Felix Pilarsky, Christian Grützmann, Robert |
author_facet | Rückert, Felix Pilarsky, Christian Grützmann, Robert |
author_sort | Rückert, Felix |
collection | PubMed |
description | The low prevalence of pancreatic cancer remains an obstacle to the development of effective screening tools in an asymptomatic population. However, development of effective serologic markers still offers the potential for improvement of diagnostic capabilities, especially for subpopulations of patients with high risk for pancreatic cancer. The accurate identification of patients with pancreatic cancer and the exclusion of disease in those with benign disorders remain important goals. While clinical experience largely dismissed many candidate markers as useful markers of pancreatic cancer, CA19-9 continues to show promise. The present review highlights the development and the properties of different tumor markers in pancreatic cancer and their impact on the diagnostic and treatment of this aggressive disease. |
format | Online Article Text |
id | pubmed-3835121 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-38351212013-11-21 Serum Tumor Markers in Pancreatic Cancer—Recent Discoveries Rückert, Felix Pilarsky, Christian Grützmann, Robert Cancers (Basel) Review The low prevalence of pancreatic cancer remains an obstacle to the development of effective screening tools in an asymptomatic population. However, development of effective serologic markers still offers the potential for improvement of diagnostic capabilities, especially for subpopulations of patients with high risk for pancreatic cancer. The accurate identification of patients with pancreatic cancer and the exclusion of disease in those with benign disorders remain important goals. While clinical experience largely dismissed many candidate markers as useful markers of pancreatic cancer, CA19-9 continues to show promise. The present review highlights the development and the properties of different tumor markers in pancreatic cancer and their impact on the diagnostic and treatment of this aggressive disease. MDPI 2010-06-02 /pmc/articles/PMC3835121/ /pubmed/24281109 http://dx.doi.org/10.3390/cancers2021107 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an Open Access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Rückert, Felix Pilarsky, Christian Grützmann, Robert Serum Tumor Markers in Pancreatic Cancer—Recent Discoveries |
title | Serum Tumor Markers in Pancreatic Cancer—Recent Discoveries |
title_full | Serum Tumor Markers in Pancreatic Cancer—Recent Discoveries |
title_fullStr | Serum Tumor Markers in Pancreatic Cancer—Recent Discoveries |
title_full_unstemmed | Serum Tumor Markers in Pancreatic Cancer—Recent Discoveries |
title_short | Serum Tumor Markers in Pancreatic Cancer—Recent Discoveries |
title_sort | serum tumor markers in pancreatic cancer—recent discoveries |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835121/ https://www.ncbi.nlm.nih.gov/pubmed/24281109 http://dx.doi.org/10.3390/cancers2021107 |
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