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Blood-brain barrier impairment in MPS III patients
BACKGROUND: Mucopolysaccharidosis type III (MPS III) is an autosomal recessive disorder caused by deficiency of a specific enzyme leading to heparan sulfate (HS) accumulation within cells and to eventual progressive cerebral and systemic organ abnormalities. Different enzyme deficiencies comprise th...
Autores principales: | Garbuzova-Davis, Svitlana, Mirtyl, Santhia, Sallot, Sebastian A, Hernandez-Ontiveros, Diana G, Haller, Edward, Sanberg, Paul R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835134/ https://www.ncbi.nlm.nih.gov/pubmed/24225396 http://dx.doi.org/10.1186/1471-2377-13-174 |
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