MnSOD(tg) Mice Control Myocardial Inflammatory and Oxidative Stress and Remodeling Responses Elicited in Chronic Chagas Disease

BACKGROUND: We utilized genetically modified mice equipped with a variable capacity to scavenge mitochondrial and cellular reactive oxygen species to investigate the pathological significance of oxidative stress in Chagas disease. METHODS AND RESULTS: C57BL/6 mice (wild type, MnSOD(tg), MnSOD(+/−),...

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Detalles Bibliográficos
Autores principales: Dhiman, Monisha, Wan, Xianxiu, Popov, Vsevolod L., Vargas, Gracie, Garg, Nisha Jain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835234/
https://www.ncbi.nlm.nih.gov/pubmed/24136392
http://dx.doi.org/10.1161/JAHA.113.000302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835234/
https://www.ncbi.nlm.nih.gov/pubmed/24136392
http://dx.doi.org/10.1161/JAHA.113.000302

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