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MnSOD(tg) Mice Control Myocardial Inflammatory and Oxidative Stress and Remodeling Responses Elicited in Chronic Chagas Disease
BACKGROUND: We utilized genetically modified mice equipped with a variable capacity to scavenge mitochondrial and cellular reactive oxygen species to investigate the pathological significance of oxidative stress in Chagas disease. METHODS AND RESULTS: C57BL/6 mice (wild type, MnSOD(tg), MnSOD(+/−),...
Autores principales: | Dhiman, Monisha, Wan, Xianxiu, Popov, Vsevolod L., Vargas, Gracie, Garg, Nisha Jain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835234/ https://www.ncbi.nlm.nih.gov/pubmed/24136392 http://dx.doi.org/10.1161/JAHA.113.000302 |
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