Survival of >20 years in a myeloma patient with an unusual combination of t(14;16) and hyperdiploidy: A case report

The current case report presents the prolonged survival of >20 years in a myeloma patient with secondary plasma cell leukemia and myelomatous pleural effusion. FISH on marrow plasma cells showed hyperdiploidy and concomitant t(14;16) and karyotypes predicting superior and short survival. The poss...

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Detalles Bibliográficos
Autores principales: CHIM, CHOR SANG, MA, EDMOND SIU KWAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835310/
https://www.ncbi.nlm.nih.gov/pubmed/24273603
http://dx.doi.org/10.3892/ol.2013.1624
Descripción
Sumario:The current case report presents the prolonged survival of >20 years in a myeloma patient with secondary plasma cell leukemia and myelomatous pleural effusion. FISH on marrow plasma cells showed hyperdiploidy and concomitant t(14;16) and karyotypes predicting superior and short survival. The possibility of primary hyperdiploidy with t(14;16) as a secondary event has been discussed.

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