Loss of the Cytoskeletal Protein Pdlim7 Predisposes Mice to Heart Defects and Hemostatic Dysfunction

The actin-associated protein Pdlim7 is essential for heart and fin development in zebrafish; however, the expression and function of this PDZ-LIM family member in the mammal has remained unclear. Here, we show that Pdlim7 predominantly localizes to actin-rich structures in mice including the heart,...

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Detalles Bibliográficos
Autores principales: Krcmery, Jennifer, Gupta, Rajesh, Sadleir, Rudyard W., Ahrens, Molly J., Misener, Sol, Kamide, Christine, Fitchev, Philip, Losordo, Douglas W., Crawford, Susan E., Simon, Hans-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835322/
https://www.ncbi.nlm.nih.gov/pubmed/24278323
http://dx.doi.org/10.1371/journal.pone.0080809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835322/
https://www.ncbi.nlm.nih.gov/pubmed/24278323
http://dx.doi.org/10.1371/journal.pone.0080809

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