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The Use of Carbon Nanotubes to Reinforce 45S5 Bioglass-Based Scaffolds for Tissue Engineering Applications

Bioglass has been used for bone-filling material in bone tissue engineering, but its lean mechanical strength limits its applications in load-bearing positions. Carbon nanotubes (CNTs), with their high aspect ratio and excellent mechanical properties, have the potential to strengthen and toughen bio...

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Autores principales: Touri, R., Moztarzadeh, F., Sadeghian, Z., Bizari, D., Tahriri, M., Mozafari, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835357/
https://www.ncbi.nlm.nih.gov/pubmed/24294609
http://dx.doi.org/10.1155/2013/465086
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author Touri, R.
Moztarzadeh, F.
Sadeghian, Z.
Bizari, D.
Tahriri, M.
Mozafari, M.
author_facet Touri, R.
Moztarzadeh, F.
Sadeghian, Z.
Bizari, D.
Tahriri, M.
Mozafari, M.
author_sort Touri, R.
collection PubMed
description Bioglass has been used for bone-filling material in bone tissue engineering, but its lean mechanical strength limits its applications in load-bearing positions. Carbon nanotubes (CNTs), with their high aspect ratio and excellent mechanical properties, have the potential to strengthen and toughen bioactive glass material without offsetting its bioactivity. Therefore, in this research, multiwall carbon nanotube (MWCNT)/45S5 Bioglass composite scaffolds have been successfully prepared by means of freeze casting process. 45S5 Bioglass was synthesized by the sol-gel processing method. The obtained material was characterized with X-ray powder diffraction (XRD). The mechanical properties of the scaffolds, such as compression strength and elastic modulus, were measured. Finally, compared with the scaffolds prepared by 100% 45S5 Bioglass powders, the addition of 0.25 wt.% MWCNTs increases the compressive strength and elastic modulus of 45S5 Bioglass scaffolds from 2.08 to 4.56 MPa (a 119% increase) and 111.50 to 266.59 MPa (a 139% increase), respectively.
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spelling pubmed-38353572013-12-01 The Use of Carbon Nanotubes to Reinforce 45S5 Bioglass-Based Scaffolds for Tissue Engineering Applications Touri, R. Moztarzadeh, F. Sadeghian, Z. Bizari, D. Tahriri, M. Mozafari, M. Biomed Res Int Research Article Bioglass has been used for bone-filling material in bone tissue engineering, but its lean mechanical strength limits its applications in load-bearing positions. Carbon nanotubes (CNTs), with their high aspect ratio and excellent mechanical properties, have the potential to strengthen and toughen bioactive glass material without offsetting its bioactivity. Therefore, in this research, multiwall carbon nanotube (MWCNT)/45S5 Bioglass composite scaffolds have been successfully prepared by means of freeze casting process. 45S5 Bioglass was synthesized by the sol-gel processing method. The obtained material was characterized with X-ray powder diffraction (XRD). The mechanical properties of the scaffolds, such as compression strength and elastic modulus, were measured. Finally, compared with the scaffolds prepared by 100% 45S5 Bioglass powders, the addition of 0.25 wt.% MWCNTs increases the compressive strength and elastic modulus of 45S5 Bioglass scaffolds from 2.08 to 4.56 MPa (a 119% increase) and 111.50 to 266.59 MPa (a 139% increase), respectively. Hindawi Publishing Corporation 2013 2013-11-04 /pmc/articles/PMC3835357/ /pubmed/24294609 http://dx.doi.org/10.1155/2013/465086 Text en Copyright © 2013 R. Touri et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Touri, R.
Moztarzadeh, F.
Sadeghian, Z.
Bizari, D.
Tahriri, M.
Mozafari, M.
The Use of Carbon Nanotubes to Reinforce 45S5 Bioglass-Based Scaffolds for Tissue Engineering Applications
title The Use of Carbon Nanotubes to Reinforce 45S5 Bioglass-Based Scaffolds for Tissue Engineering Applications
title_full The Use of Carbon Nanotubes to Reinforce 45S5 Bioglass-Based Scaffolds for Tissue Engineering Applications
title_fullStr The Use of Carbon Nanotubes to Reinforce 45S5 Bioglass-Based Scaffolds for Tissue Engineering Applications
title_full_unstemmed The Use of Carbon Nanotubes to Reinforce 45S5 Bioglass-Based Scaffolds for Tissue Engineering Applications
title_short The Use of Carbon Nanotubes to Reinforce 45S5 Bioglass-Based Scaffolds for Tissue Engineering Applications
title_sort use of carbon nanotubes to reinforce 45s5 bioglass-based scaffolds for tissue engineering applications
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835357/
https://www.ncbi.nlm.nih.gov/pubmed/24294609
http://dx.doi.org/10.1155/2013/465086
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