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Lung Collagens Perpetuate Pulmonary Fibrosis via CD204 and M2 Macrophage Activation

Idiopathic pulmonary fibrosis is characterized by abundant collagen production and accumulation of alternatively activated macrophages (M2) in the lower respiratory tract. Mechanisms as to how alveolar macrophages are activated by collagen breakdown products are unknown. Alveolar macrophages were ob...

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Detalles Bibliográficos
Autores principales: Stahl, Mirjam, Schupp, Jonas, Jäger, Benedikt, Schmid, Michael, Zissel, Gernot, Müller-Quernheim, Joachim, Prasse, Antje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835428/
https://www.ncbi.nlm.nih.gov/pubmed/24278429
http://dx.doi.org/10.1371/journal.pone.0081382