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Lung Collagens Perpetuate Pulmonary Fibrosis via CD204 and M2 Macrophage Activation
Idiopathic pulmonary fibrosis is characterized by abundant collagen production and accumulation of alternatively activated macrophages (M2) in the lower respiratory tract. Mechanisms as to how alveolar macrophages are activated by collagen breakdown products are unknown. Alveolar macrophages were ob...
Autores principales: | Stahl, Mirjam, Schupp, Jonas, Jäger, Benedikt, Schmid, Michael, Zissel, Gernot, Müller-Quernheim, Joachim, Prasse, Antje |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835428/ https://www.ncbi.nlm.nih.gov/pubmed/24278429 http://dx.doi.org/10.1371/journal.pone.0081382 |
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