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Infectious Agents in the Pathogenesis of Primary Biliary Cirrhosis

Primary biliary cirrhosis (PBC) is a chronic progressive cholestatic liver disease which is characterized by the breakdown of self-tolerance to the highly conserved pyruvate dehydrogenase complex, specially the pyruvate dehydrogenase E2 complex (PDC-E2). The breakdown of the tolerance to such antige...

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Detalles Bibliográficos
Autores principales: Ortega-Hernandez, Oscar-Danilo, Levin, Nancy-Agmon, Altman, Arie, Shoenfeld, Yehuda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835533/
https://www.ncbi.nlm.nih.gov/pubmed/21297247
http://dx.doi.org/10.3233/DMA-2010-0771