Category-specific integration of homeostatic signals in caudal, but not rostral, human insula

Prevailing theories hold that the insula is functionally organized along its caudal-to-rostral axis, with posterior regions coding lower-level sensory information, and anterior regions coding higher-level stimulus significance relative to the body’s homeostatic needs. Contrary to predictions of this...

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Autores principales: Simmons, W. Kyle, Rapuano, Kristina M., Kallman, Seth J., Ingeholm, John E., Miller, Bernard, Gotts, Stephen J., Avery, Jason A., Hall, Kevin D., Martin, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835665/
https://www.ncbi.nlm.nih.gov/pubmed/24077565
http://dx.doi.org/10.1038/nn.3535
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author Simmons, W. Kyle
Rapuano, Kristina M.
Kallman, Seth J.
Ingeholm, John E.
Miller, Bernard
Gotts, Stephen J.
Avery, Jason A.
Hall, Kevin D.
Martin, Alex
author_facet Simmons, W. Kyle
Rapuano, Kristina M.
Kallman, Seth J.
Ingeholm, John E.
Miller, Bernard
Gotts, Stephen J.
Avery, Jason A.
Hall, Kevin D.
Martin, Alex
author_sort Simmons, W. Kyle
collection PubMed
description Prevailing theories hold that the insula is functionally organized along its caudal-to-rostral axis, with posterior regions coding lower-level sensory information, and anterior regions coding higher-level stimulus significance relative to the body’s homeostatic needs. Contrary to predictions of this model, the response of the taste-sensitive region of the caudal, but not rostral, insula to food images was directly related to the body’s homeostatic state as indexed by levels of peripheral glucose.
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spelling pubmed-38356652014-05-01 Category-specific integration of homeostatic signals in caudal, but not rostral, human insula Simmons, W. Kyle Rapuano, Kristina M. Kallman, Seth J. Ingeholm, John E. Miller, Bernard Gotts, Stephen J. Avery, Jason A. Hall, Kevin D. Martin, Alex Nat Neurosci Article Prevailing theories hold that the insula is functionally organized along its caudal-to-rostral axis, with posterior regions coding lower-level sensory information, and anterior regions coding higher-level stimulus significance relative to the body’s homeostatic needs. Contrary to predictions of this model, the response of the taste-sensitive region of the caudal, but not rostral, insula to food images was directly related to the body’s homeostatic state as indexed by levels of peripheral glucose. 2013-09-29 2013-11 /pmc/articles/PMC3835665/ /pubmed/24077565 http://dx.doi.org/10.1038/nn.3535 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Simmons, W. Kyle
Rapuano, Kristina M.
Kallman, Seth J.
Ingeholm, John E.
Miller, Bernard
Gotts, Stephen J.
Avery, Jason A.
Hall, Kevin D.
Martin, Alex
Category-specific integration of homeostatic signals in caudal, but not rostral, human insula
title Category-specific integration of homeostatic signals in caudal, but not rostral, human insula
title_full Category-specific integration of homeostatic signals in caudal, but not rostral, human insula
title_fullStr Category-specific integration of homeostatic signals in caudal, but not rostral, human insula
title_full_unstemmed Category-specific integration of homeostatic signals in caudal, but not rostral, human insula
title_short Category-specific integration of homeostatic signals in caudal, but not rostral, human insula
title_sort category-specific integration of homeostatic signals in caudal, but not rostral, human insula
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835665/
https://www.ncbi.nlm.nih.gov/pubmed/24077565
http://dx.doi.org/10.1038/nn.3535
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