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A Rad53 Independent Function of Rad9 Becomes Crucial for Genome Maintenance in the Absence of the RecQ Helicase Sgs1
The conserved family of RecQ DNA helicases consists of caretaker tumour suppressors, that defend genome integrity by acting on several pathways of DNA repair that maintain genome stability. In budding yeast, Sgs1 is the sole RecQ helicase and it has been implicated in checkpoint responses, replisome...
Autores principales: | Nielsen, Ida, Bentsen, Iben Bach, Andersen, Anni H., Gasser, Susan M., Bjergbaek, Lotte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835667/ https://www.ncbi.nlm.nih.gov/pubmed/24278365 http://dx.doi.org/10.1371/journal.pone.0081015 |
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