Integrative Analysis of Hereditary Nonpolyposis Colorectal Cancer: the Contribution of Allele-Specific Expression and Other Assays to Diagnostic Algorithms

The identification of germline variants predisposing to hereditary nonpolyposis colorectal cancer (HNPCC) is crucial for clinical management of carriers, but several probands remain negative for such variants or bear variants of uncertain significance (VUS). Here we describe the results of integrati...

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Detalles Bibliográficos
Autores principales: De Lellis, Laura, Aceto, Gitana Maria, Curia, Maria Cristina, Catalano, Teresa, Mammarella, Sandra, Veschi, Serena, Fantini, Fabiana, Battista, Pasquale, Stigliano, Vittoria, Messerini, Luca, Mareni, Cristina, Sala, Paola, Bertario, Lucio, Radice, Paolo, Cama, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835792/
https://www.ncbi.nlm.nih.gov/pubmed/24278394
http://dx.doi.org/10.1371/journal.pone.0081194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835792/
https://www.ncbi.nlm.nih.gov/pubmed/24278394
http://dx.doi.org/10.1371/journal.pone.0081194

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