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Antioxidative and Anticholinesterase Activity of Cyphomandra betacea Fruit

Cyphomandra betacea is one of the underutilized fruits which can be found in tropical and subtropical countries. This study was conducted to determine the antioxidant activity and phytochemical contents in different parts (i.e., flesh and peel) of the fruits. Antioxidants were analyzed using DPPH an...

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Autores principales: Ali Hassan, Siti Hawa, Abu Bakar, Mohd Fadzelly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835838/
https://www.ncbi.nlm.nih.gov/pubmed/24298210
http://dx.doi.org/10.1155/2013/278071
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author Ali Hassan, Siti Hawa
Abu Bakar, Mohd Fadzelly
author_facet Ali Hassan, Siti Hawa
Abu Bakar, Mohd Fadzelly
author_sort Ali Hassan, Siti Hawa
collection PubMed
description Cyphomandra betacea is one of the underutilized fruits which can be found in tropical and subtropical countries. This study was conducted to determine the antioxidant activity and phytochemical contents in different parts (i.e., flesh and peel) of the fruits. Antioxidants were analyzed using DPPH and ABTS free radical scavenging assays as well as FRAP assay. Anticholinesterase activity was determined using enzymatic assay using acetyl cholinesterase enzyme. For 80% methanol extract, the peel of the fruit displayed higher antioxidant activity in both FRAP and ABTS free radical scavenging assays while the flesh displayed higher antioxidant activity in the DPPH assay. Total phenolic and total flavonoid content were higher in the peel with the values of 4.89 ± 0.04 mg gallic acid equivalent (GAE)/g and 3.36 ± 0.01 mg rutin equivalent (RU)/g, respectively. Total anthocyanin and carotenoid content were higher in the flesh of the fruit with the values of 4.15 ± 0.04 mg/100 g and 25.13 ± 0.35 mg/100 g. The anticholinesterase was also higher in the peel of C. betacea. The same trends of phytochemicals, antioxidant, and anticholinesterase were also observed in the distilled water extracts. These findings suggested that C. betacea has a potential as natural antioxidant-rich nutraceutical products.
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spelling pubmed-38358382013-12-02 Antioxidative and Anticholinesterase Activity of Cyphomandra betacea Fruit Ali Hassan, Siti Hawa Abu Bakar, Mohd Fadzelly ScientificWorldJournal Research Article Cyphomandra betacea is one of the underutilized fruits which can be found in tropical and subtropical countries. This study was conducted to determine the antioxidant activity and phytochemical contents in different parts (i.e., flesh and peel) of the fruits. Antioxidants were analyzed using DPPH and ABTS free radical scavenging assays as well as FRAP assay. Anticholinesterase activity was determined using enzymatic assay using acetyl cholinesterase enzyme. For 80% methanol extract, the peel of the fruit displayed higher antioxidant activity in both FRAP and ABTS free radical scavenging assays while the flesh displayed higher antioxidant activity in the DPPH assay. Total phenolic and total flavonoid content were higher in the peel with the values of 4.89 ± 0.04 mg gallic acid equivalent (GAE)/g and 3.36 ± 0.01 mg rutin equivalent (RU)/g, respectively. Total anthocyanin and carotenoid content were higher in the flesh of the fruit with the values of 4.15 ± 0.04 mg/100 g and 25.13 ± 0.35 mg/100 g. The anticholinesterase was also higher in the peel of C. betacea. The same trends of phytochemicals, antioxidant, and anticholinesterase were also observed in the distilled water extracts. These findings suggested that C. betacea has a potential as natural antioxidant-rich nutraceutical products. Hindawi Publishing Corporation 2013-11-03 /pmc/articles/PMC3835838/ /pubmed/24298210 http://dx.doi.org/10.1155/2013/278071 Text en Copyright © 2013 S. H. Ali Hassan and M. F. Abu Bakar. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Ali Hassan, Siti Hawa
Abu Bakar, Mohd Fadzelly
Antioxidative and Anticholinesterase Activity of Cyphomandra betacea Fruit
title Antioxidative and Anticholinesterase Activity of Cyphomandra betacea Fruit
title_full Antioxidative and Anticholinesterase Activity of Cyphomandra betacea Fruit
title_fullStr Antioxidative and Anticholinesterase Activity of Cyphomandra betacea Fruit
title_full_unstemmed Antioxidative and Anticholinesterase Activity of Cyphomandra betacea Fruit
title_short Antioxidative and Anticholinesterase Activity of Cyphomandra betacea Fruit
title_sort antioxidative and anticholinesterase activity of cyphomandra betacea fruit
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835838/
https://www.ncbi.nlm.nih.gov/pubmed/24298210
http://dx.doi.org/10.1155/2013/278071
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